medicine

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Malaria drug resistance in humans and mosquitoes

in medicine, biology

Researchers have detected contrasting patterns of drug resistance in malaria-causing parasites taken from both humans and mosquitoes in rural Zambia. Parasites found in human blood samples showed a high prevalence for pyrimethamine-resistance, which was consistent with the class of drugs widely used to treat malaria in the region.

Why do neurons die in Parkinson's disease?

in medicine, biology

A new study shows that genetic mutations causing a hereditary form of Parkinson's disease cause a cellular organalle, mitochondria, to run amok inside the cell, leaving the cell without a brake to stop them.

How Headache Tree Causes Cluster Headache and Migraine

in medicine, biology

Researchers have now identified the mechanism by which the plant California laurel, also known as headache tree, causes headache and migraine. They discovered that headache is caused when a bioactive compound released from the leaves of this plant triggers a cascade of chemical events in trigeminal nerves around head arteries. 

Metabolic protein plays unexpected role in tumor cell formation and growth

in medicine, biology

New findingsindings point to possible personalized brain tumor therapy with Src inhibitors. The embryonic enzyme pyruvate kinase M2 (PKM2) has a well-established role in metabolism and is highly expressed in human cancers.

Brains Come Wired for Cooperation

in medicine, biology

The brain is built for cooperative activity, whether it be dancing on a reality television show, constructing a skyscraper or  working in an office, according to a study led by Johns Hopkins behavioral neuroscientist Eric Fortune and published in the November 4 issue of the journal Science.

Lung regeneration closer to reality?

in medicine

Researchers reports that they have uncovered the biochemical signals in mice that trigger generation of new lung alveoli, the numerous, tiny, grape-like sacs within the lung where oxygen exchange takes place. Specifically, the regenerative signals originate from the specialized endothelial cells that line the interior of blood vessels in the lung.

New Pathway Critical to Heart Arrhythmia

in medicine, biology

Researchers have uncovered a previously unknown molecular pathway that is critical to understanding cardiac arrhythmia and other heart muscle problems. Understanding the basic science of heart and muscle function could open the door to new treatments. 

CK1 protein possible cancer therapeutic target

in medicine

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells. The study shows the significant role that protein networks can play in a cell leading to the development of cancer.