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Face transplant at University of Maryland - The transplant included jaws, teeth and tongue

in medicine, biology

In a remarkable 36-hour operation transplant surgeons at the University of Maryland performed the most extensive full face transplant.  The face transplant included both jaws, teeth and tongue.  This marks the first time in the world that a full face transplant was performed by a team of plastic and reconstructive surgeons with specialized training and expertise in craniofacial surger

PCSK9 monoclonal antibody REGN727- a new drug to lower LDL Cholesetrol?

in medicine

According to a new study, a monoclonal antibody (REGN727) to the protein PCSK9 can significantly reduce bad cholesterol.  PCSK9 (proprotein convertase subtilisin/kexin 9) is a serine protease.  LDL cholesterol levels in the blood increases when its receptors (LDL receptor) are degraded by binding to PCSK9.

NIH Budget 2013 - Sign the Petition to Increase the NIH Budget

in medicine

A petition to increase NIH budget to $33 billion dollars in 2012-2013 fiscal year is under way. According to the petition being promoted on the White House website, a flat $30.7 billion funding for the year will kill jobs and hurt research.

Vitamin D May Help Clear Amyloid Plaques Found in Alzheimer's - Mechanism Revealed

in medicine

Researchers have identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta. Amyloid beta is the main component of plaques associated with Alzheimer's disease. Amyloid beta, also called Abeta, is a peptide of 36–43 amino acids long that is cleaved from the parent peptide,  Amyloid precursor protein.

Children with autism have a different type of gut bacteria

in medicine

Gastrointestinal problems are common in children with autism and may be associated with compositional changes in intestinal bacteria. The underlying reason autism is often associated with gastrointestinal disturbances has been unknown.

3-D world in our brains - neuron-by-neuron maps of the regions of the mouse brain

in medicine, biology

For the first time, the scientists have produced neuron-by-neuron maps of the regions of the mouse brain that process different kinds of visual information, laying the groundwork for decoding the circuitry of the brain using cutting-edge, genetic research techniques only possible in mice.

Ritalin Targets Prefrontal Cortex in Attention Deficit Hyperactivity Disorder (ADHD) Patients

in medicine, biology

The psychostimulant methylphenidate, known by the brand name Ritalin, is used as part of a treatment program to the control symptoms of attention deficit hyperactivity disorder (ADHD).  Symptoms of ADHD starts before the age of seven years and  affects about 3 to 5 percent of children world-wide. Millions of individuals diagnosed with ADHD are treated by Ritalin.

Human artificial chromosome-based vectors in gene therapy

in medicine, biology, omics

In a new research report scientists now describe a combination of direct gene-cloning technology with the human artificial chromosome- based vector for gene delivery. Gene delivery, one of the steps necessary for gene therapy, is the process of introducing foreign genes into host cells.