NIH-Funding

Formative and Pilot Intervention Research for Prevention and Treatment of HIV/AIDS (R34 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 12:03
Funding Opportunity PA-18-276 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages formative research, intervention development, and pilot-testing of interventions. Primary scientific areas of focus include the feasibility, tolerability, acceptability and safety of novel or adapted interventions that target HIV prevention or treatment. For the purposes of this FOA, intervention is defined to include behavioral, social, or structural approaches, as well as combination biomedical and behavioral, social, or structural approaches that prevent acquisition and transmission of HIV infection, or improve clinical outcomes for persons who are HIV infected, or both.
Categories: NIH-Funding

Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 12:01
Funding Opportunity PAR-18-190 from the NIH Guide for Grants and Contracts. This FOA encourages exploratory/developmental research applications at the intersection of HIV and aging by addressing two overarching objectives: 1) to improve understanding of biological, clinical, and socio-behavioral aspects of aging through the lens of HIV infection and its treatment; and 2) to improve approaches for testing, prevention, and treatment of HIV infection, and management of HIV-related comorbidities, co-infections, and complications in different populations and cultural settings by applying our current understanding of aging science. Applications appropriate to this FOA should be consistent with the scientific priorities outlined by the NIH Office of AIDS Research (OAR) as described in NOT-OD-15-137.
Categories: NIH-Funding

Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 11:56
Funding Opportunity PAR-18-189 from the NIH Guide for Grants and Contracts. This FOA encourages applications at the intersection of HIV and aging by addressing two overarching objectives: 1) to improve understanding of biological, clinical, and socio-behavioral aspects of aging through the lens of HIV infection and its treatment; and 2) to improve approaches for testing, prevention, and treatment of HIV infection, and management of HIV-related comorbidities, co-infections, and complications in different populations and cultural settings by applying our current understanding of aging science. Applications appropriate to this FOA should be consistent with the scientific priorities outlined by the NIH Office of AIDS Research (OAR) as described in NOT-OD-15-137.
Categories: NIH-Funding

Increased Knowledge and Innovative Strategies to Reduce HIV Incidence-iKnow Projects (R01 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 11:54
Funding Opportunity PAR-18-254 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to promote innovative research that addresses one or both of the following objectives: Devise optimal strategies to improve the identification of persons unaware of their HIV-1 infection and successfully link them to HIV testing, treatment, and prevention interventions. Develop and examine the feasibility and acceptability of novel integrated interventions of biomedical and behavioral strategies that substantially reduce the likelihood of onward HIV transmission in these populations.
Categories: NIH-Funding

Fast-Track Development of Medications to Treat Cannabis Use Disorders (UG3/UH3 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 11:52
Funding Opportunity PAR-18-221 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to accelerate the discovery and development of medications to treat Cannabis Use Disorders (CUDs) using the UG3/UH3 mechanism. The objective is to advance medications toward the ultimate goal of obtaining FDA approval. Advances in understanding the cannabinoid systems and the effects of marijuana on the brain, coupled with the availability of both novel and marketed medications that may be efficacious to treat these disorders, offer unprecedented opportunities to develop safe and effective pharmacotherapies for CUDs.
Categories: NIH-Funding

NICHD Research Education Programs (R25 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 11:50
Funding Opportunity PAR-18-217 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NICHD R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs.
Categories: NIH-Funding

Innovations in Mechanisms and Interventions to Address Mental Health in HIV Prevention and Care Continuum (R21 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 11:36
Funding Opportunity PA-18-275 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications focused on 1) advancing understanding of mechanisms by which mental health affects HIV prevention and treatment in order to identify modifiable intervention targets; and 2) developing and pilot testing expanded interventions to improve both mental health and HIV outcomes along the entire HIV care continuum (from HIV testing to viral suppression). PA-17-NNN uses the R01 grant mechanism while PA-17-NN uses the R21 mechanism. High risk/high payoff projects that lack preliminary data or utilize existing data may be most appropriate for the R21 mechanism, while applicants with preliminary data and/or include longitudinal analysis may wish to apply using the R01 mechanism.
Categories: NIH-Funding

Innovations in Mechanisms and Interventions to Address Mental Health in HIV Prevention and Care Continuum (R01 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 11:32
Funding Opportunity PA-18-274 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications focused on 1) advancing understanding of mechanisms by which mental health affects HIV prevention and treatment in order to identify modifiable intervention targets; and 2) developing and testing expanded interventions to improve both mental health and HIV outcomes along the entire HIV care continuum (from HIV testing to viral suppression). PA-17-136 uses the R01 grant mechanism while PA-17-137 uses the R21 mechanism. High risk/high payoff projects that lack preliminary data or utilize existing data may be most appropriate for the R21 mechanism, while applicants with preliminary data and/or include longitudinal analysis may wish to apply using the R01 mechanism.
Categories: NIH-Funding

Targeted basic behavioral and social science and intervention development for HIV prevention and care (R01 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 11:29
Funding Opportunity PA-18-273 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits innovative, targeted basic behavioral and social science and intervention development research to reduce incident HIV infections and improve the health of those living with HIV. This FOA encourages research designed to (a) conduct basic behavioral and social science research that is needed to advance the development of HIV prevention and care interventions, (b) translate and operationalize the findings from these basic studies to develop interventions and assess their acceptability and feasibility and (c) conduct tests of the efficacy of HIV prevention and care interventions. This FOA uses the R01 grant mechanism while PA-18-272 uses the R21 mechanism.
Categories: NIH-Funding

Targeted basic behavioral and social science and intervention development for HIV prevention and care (R21 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 11:26
Funding Opportunity PA-18-272 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages innovative, targeted basic behavioral and social science and intervention development research to reduce incident HIV infections and improve the health of those living with HIV. This FOA encourages research designed to (a) conduct basic behavioral and social science research that is needed to advance the development of HIV prevention and care interventions, (b) translate and operationalize the findings from these basic studies to develop interventions and assess their acceptability and feasibility and (c) conduct tests of the efficacy of HIV prevention and care interventions. PA-17-106 uses the R01 grant mechanism while this FOA uses the R21 mechanism. High risk/high payoff projects that lack preliminary data or utilize existing data may be most appropriate for the R21 mechanism, while applicants with preliminary data and/or include longitudinal analysis may wish to apply using the R01 mechanism.
Categories: NIH-Funding

Strengthening the HIV Pre-Exposure Prophylaxis (PrEP) Care Continuum through Behavioral, Social, and Implementation Science (R21 Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 11:18
Funding Opportunity PA-18-271 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages behavioral, social, and implementation science research designed to (a) identify gaps in the HIV pre-exposure prophylaxis (PrEP) care continuum and associated determinants; (b) develop and test interventions to strengthen PrEP delivery, use, and outcomes; and (c) reduce racial/ethnic and age-related disparities in PrEP uptake and use.
Categories: NIH-Funding

NIH Pathway to Independence Award (Parent K99/R00 - Clinical Trial Required)

NIH Funding Announcements - Wed, 11/29/2017 - 05:19
Funding Opportunity PA-18-397 from the NIH Guide for Grants and Contracts. The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary study to an existing trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion FOA (PA-18-398).
Categories: NIH-Funding

NIH Pathway to Independence Award (Parent K99/R00 - Independent Clinical Trial Not Allowed)

NIH Funding Announcements - Wed, 11/29/2017 - 05:19
Funding Opportunity PA-18-398 from the NIH Guide for Grants and Contracts. The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary study to an ongoing clinical trial as lead investigator, should apply to the companion FOA (PA-18-397).
Categories: NIH-Funding

NIDA Program Project Grant Applications (P01, Clinical Trial Optional)

NIH Funding Announcements - Wed, 11/29/2017 - 04:50
Funding Opportunity PAR-18-425 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) announces the availability of support for collaborative research by multi-disciplinary teams which is of high priority to NIDA and leads to synergistic outcomes based on the synthesis of multiple research approaches. The NIDA Program Projects funding opportunity will support research in which the funding of three or more highly meritorious projects as a group enriches both the component projects and the overall program to offer significant scientific advantages over supporting the same projects as individual research grants (i.e., synergy). For the duration of the award, each Program must consist of a minimum of three research projects focused on issues critical to advance the mission and goals of NIDA.
Categories: NIH-Funding

Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 - Clinical Trials Required)

NIH Funding Announcements - Wed, 11/29/2017 - 02:39
Funding Opportunity PAR-18-417 from the NIH Guide for Grants and Contracts. The goal of this funding opportunity announcement (FOA) is to support early phase clinical trials of mind and body approaches for conditions that have been identified by NCCIH as high priority research topics. This funding opportunity is intended to support exploratory clinical trials, which will provide data that are critical for the planning and design of a subsequent controlled cohort study, clinical efficacy or effectiveness study, or a pragmatic trial. The data collected should be used to fill gaps in scientific knowledge necessary to develop a competitive full-scale clinical trial. This FOA is not appropriate for support of randomized clinical trials to test or determine efficacy or effectiveness. Applications that propose solely to write a protocol or manual of operations or to develop infrastructure for a clinical trial are not appropriate for this announcement. The subsequent larger trial should have the potential to make a significant impact on public health.
Categories: NIH-Funding