NIH Funding Announcements

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Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 14 hours 56 min ago

Planning Grant to Develop Phase III Clinical Trials for Lewy Body Dementia (R34 clinical Trial Not Allowed)

Wed, 12/06/2017 - 05:58
Funding Opportunity RFA-NS-18-017 from the NIH Guide for Grants and Contracts. The purpose of this R34 FOA is to provide one year of support for planning activities necessary for initiating a Phase III clinical trial designed to treat patients with Lewy Body Dementias (LBD), which include Dementia with Lewy Bodies and Parkinson's Disease Dementia. Such activities may include identifying trial sites/collaborators, designing trial protocols and procedures, and addressing regulatory approvals.
Categories: NIH-Funding

NICHD Exploratory/Developmental Research Grant (R21 - Clinical Trial Optional)

Wed, 12/06/2017 - 05:54
Funding Opportunity PA-18-482 from the NIH Guide for Grants and Contracts. The NICHD Exploratory/Developmental Grant program supports exploratory and developmental research projects that fall within the NICHD mission by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
Categories: NIH-Funding

NICHD Research Project Grant (R01 - Clinical Trial Required)

Wed, 12/06/2017 - 04:57
Funding Opportunity PA-18-480 from the NIH Guide for Grants and Contracts. The NICHD Research Project Grant (Clinical Trial Required) supports clinical trials that fall within the NICHD mission.
Categories: NIH-Funding

Pilot Effectiveness Trials for Post-Acute Interventions and Serivces to Optimize Longer-Term Outcomes (R34-Clinical Trials Required)

Wed, 12/06/2017 - 04:40
Funding Opportunity PAR-18-431 from the NIH Guide for Grants and Contracts. NIMH seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate service use) and intensity/burden. In this pilot phase of effectiveness research, the trial should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach; to address whether the intervention engages the target(s)/mechanisms(s) that is/are presumed to underlie the intervention effects; and to obtain preliminary data needed as a pre-requisite to a larger-scale effectiveness trial (e.g., comparative effectiveness study, practical trial) designed to definitely test the effectiveness of interventions to improve post-acute outcomes. This FOA supports pilot effectiveness research to evaluate the feasibility, tolerability, acceptability, safety and preliminary indications of effectiveness of post-acute phase intervention approaches and inform the design of definitive effectiveness trials. Support for fully-powered, definitive effectiveness studies focused on post-acute phase interventions is provided via the R01 in PAR-18-423.
Categories: NIH-Funding

Effectiveness Trials for Post-Acute Interventions and Services and Services to Optimize Longer-Term Outcomes (R01-Clinical Trials Required)

Wed, 12/06/2017 - 04:40
Funding Opportunity PAR-18-430 from the NIH Guide for Grants and Contracts. NIMH seeks applications for research projects to evaluate the effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions affecting youth, adults, and older adults. This FOA encourages clinical trials to establish the effectiveness and test hypotheses regarding moderators, mediators, and mechanisms of action of post-acute phase therapeutic and services interventions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate service use) and intensity/burden for promoting optimal longer-term outcomes. This FOA is intended to support effectiveness trials testing post-acute phase interventions that are statistically powered to provide a definitive answer regarding the study intervention's effectiveness. Support for pilot effectiveness trials to evaluate the initial feasibility, tolerability, acceptability, safety and preliminary indications of effectiveness of post-acute phase intervention approaches is provided via the R34 in PAR-18-422 .
Categories: NIH-Funding

NIH Exploratory/Developmental Research Grant Program ( Parent R21 Clinical Trial Not Allowed)

Wed, 12/06/2017 - 03:53
Funding Opportunity PA-18-489 from the NIH Guide for Grants and Contracts. The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Funding Opportunity Announcement does not accept clinical trials.
Categories: NIH-Funding

NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

Wed, 12/06/2017 - 03:35
Funding Opportunity PA-18-488 from the NIH Guide for Grants and Contracts. The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time with limited resources. This program supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. This Funding Opportunity Announcement does not accept clinical trials.
Categories: NIH-Funding

NIBIB Supplements to NCATS CTSA Programs for Translational Research Teams of Quantitative Researchers and Clinician-Scientists (Admin Supp)

Wed, 12/06/2017 - 03:18
Funding Opportunity PA-18-426 from the NIH Guide for Grants and Contracts. The purpose of this administrative supplement is to facilitate collaboration by supporting multidisciplinary research teams comprised of quantitative researchers and clinician-scientists from active CTSA institutions (PAR-15-304). This supplement will support translational team research projects by providing salary and research support to a quantitative researcher, contingent upon his/her collaborating with a clinician-scientist KL2 scholar. The collaborative KL2 clinician-scientist will be supported independently of this supplement through the parent KL2 award throughout the duration of the proposed supplement. Both team members will be selected by the KL2 PI. The KL2 PI will assist the quantitative researcher and clinician-scientist in developing a translational research project aligned with NIBIBs research mission under the guidance of their identified basic and clinical science mentors. Based on this, the KL2 PI will submit a supplement request under this FOA.
Categories: NIH-Funding

Clinical and Translational Science Award U54 (Clinical Trial Optional)

Tue, 12/05/2017 - 12:35
Funding Opportunity PAR-18-464 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to invite applications to participate in the Clinical and Translational Science Award (CTSA) program which supports high quality translational and clinical research locally, regionally and nationally and fosters innovation in research methods, training, and career development.
Categories: NIH-Funding

Pilot Studies to Test the Initiation of a Mental Health, Family Navigator Model to Promote Early Access, Engagement and Coordination of needed Mental Health Services for Children and Adolescents (R34-Clinical Trial Required)

Tue, 12/05/2017 - 11:32
Funding Opportunity PAR-18-429 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage research applications to develop and pilot test the effectiveness and implementation of family navigator models designed to promote early access, engagement and coordination of mental health treatment and services for children and adolescents who are experiencing early symptoms of mental health problems. For the purposes of this FOA, NIMH defines a family navigator model as a health care professional or paraprofessional whose role is to deploy a set of strategies designed to rapidly engage youth and families in needed treatment and services, work closely with the family and other involved treatment and service providers to optimize care and monitor the trajectory of mental health symptoms and outcomes over time. Applicants are encouraged to develop and pilot test the navigator models ability to promote early access, engagement and coordination of mental health treatment and services for children and adolescents as soon as symptoms are detected. Of interest are navigator models that coordinate needed care strategies, determine the personalized match to the level of needed service amount, frequency and intensity, and harness novel technologies to track and monitor the trajectory of clinical, functional and behavioral progress toward achieving intended services outcomes. This FOA is published in parallel to a companion FOA, PAR-18-428 which uses the R01 funding mechanism.
Categories: NIH-Funding

Initiation of a Mental Health Family Navigator Model to Promote Early Access, Engagement and Coordination of Needed Mental Health Services for Children and Adolescents (R01- Clincal Trial Required)

Tue, 12/05/2017 - 11:32
Funding Opportunity PAR-18-428 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage research applications to develop and test the effectiveness and implementation of family navigator models designed to promote early access, engagement and coordination of mental health treatment and services for children and adolescents who are experiencing early symptoms of mental health problems. For the purposes of this FOA, NIMH defines a family navigator model as a health care professional or paraprofessional whose role is to deploy a set of strategies designed to rapidly engage youth and families in needed treatment and services, work closely with the family and other involved treatment and service providers to optimize care and monitor the trajectory of mental health symptoms and outcomes over time. Applicants are encouraged to develop and test the navigator models ability to promote early access, engagement and coordination of mental health treatment and services for children and adolescents as soon as symptoms are detected. Of interest are navigator models that coordinate needed care strategies, determine the personalized match to the level of needed service amount, frequency and intensity, and harness novel technologies to track and monitor the trajectory of clinical, functional and behavioral progress toward achieving intended services outcomes. This FOA is published in parallel to a companion R34 FOA PAR-18-429 supporting pilot studies in preparation for the larger-scale studies described here.
Categories: NIH-Funding

Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional)

Tue, 12/05/2017 - 11:05
Funding Opportunity RFA-DK-18-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators as a means to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding,
Categories: NIH-Funding

NICHD Small Grant Program (R03 - Clinical Trial Optional)

Tue, 12/05/2017 - 04:03
Funding Opportunity PA-18-481 from the NIH Guide for Grants and Contracts. The NICHD Investigator-Initiated Small Research Grant (R03) funding opportunity supports small research projects that can be carried out in a short period of time with limited resources. The R03 activity code supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology.
Categories: NIH-Funding

Cancer Research Education Grants Program - Curriculum or Methods Development (R25)

Tue, 12/05/2017 - 03:13
Funding Opportunity PAR-18-476 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Curriculum or Methods Development. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, and treatment of cancer, rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients, in accordance with the overall mission of the NCI.
Categories: NIH-Funding

Cancer Research Education Grants Program - Courses for Skills Development (R25)

Tue, 12/05/2017 - 03:13
Funding Opportunity PAR-18-477 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Courses for Skills Development. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continuing care of cancer patients and the families of cancer patients
Categories: NIH-Funding