Researchers have detected contrasting patterns of drug resistance in malaria-causing parasites taken from both humans and mosquitoes in rural Zambia. Parasites found in human blood samples showed a high prevalence for pyrimethamine-resistance, which was consistent with the class of drugs widely used to treat malaria in the region.
Researchers now reveal the creative power of Foldit players' strategies and compare them to the best-known scientist-developed methods. This report follows a recent paper on solving the crystal structure of a monomeric retroviral protease by protein folding game players.
A new study shows that genetic mutations causing a hereditary form of Parkinson's disease cause a cellular organalle, mitochondria, to run amok inside the cell, leaving the cell without a brake to stop them.
The two-faced Roman god Janus has inspired a class of unique particles that possess two different sides or surfaces of different chemistry or polarity. Researchers now report the synthesis of three different Janus topologies from one single specific triblock copolymer.
Researchers have now identified the mechanism by which the plant California laurel, also known as headache tree, causes headache and migraine. They discovered that headache is caused when a bioactive compound released from the leaves of this plant triggers a cascade of chemical events in trigeminal nerves around head arteries.
Scientists now report the synthesis of the most complex non-DNA molecular knot prepared to date. They created a 160-atom-loop with five crossing points, a molecular pentafoil knot. The molecular knot created is a self-assembly of five bis-aldehyde and five bis-amine building blocks about five metal cations (Iron) and one chloride anion.
New findingsindings point to possible personalized brain tumor therapy with Src inhibitors. The embryonic enzyme pyruvate kinase M2 (PKM2) has a well-established role in metabolism and is highly expressed in human cancers.
In one of the first applications of atomic force microscopy to the study of tissue and cell mechanics in development, a team of scientists from France and Switzerland linked the changes in cell wall mechanics and chemical modifications of the cell wall structure to organ emergence and patterning.